The beta-glucosidase antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GBA, GBA1, GCB, glucocerebrosidase, and Miscellaneous. This antibody recognizes Human antigen. The beta-glucosidase antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]